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Answer -
As a result of denaturation, globules get unfolded andhelixes get uncoiled. Secondary and tertiary structures of protein aredestroyed, but the primary structures remain unaltered. It can be said thatduring denaturation, secondary and tertiary-structured proteins get convertedinto primary-structured proteins. Also, as the secondary and tertiarystructures of a protein are destroyed, the enzyme loses its activity.