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Oxidative phosphorylation is a process inwhich electrons are transferred from electron donors to oxygen, which acts aselectron acceptor. The oxidation-reduction reactions are involved in theformation of proton gradient. The main role in oxidative phosphorylation isplayed by the enzyme ATP synthase (complex V). This enzyme complex consists of F0 and F1 components.The F1 headpiece is a peripheral membrane proteincomplex and contains the site for ATP synthesis from ADP and inorganicphosphate. F0 component is a part of membrane proteincomplex, which acts as a channel for crossing of the protons from innermitochondrial membrane to the mitochondrial matrix. For every two protonspassing through F0–F1 complex, synthesis of one ATP molecule takesplace.