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Question -

Define oxygen dissociation curve. Can you suggest any reason for its sigmoidal pattern?



Answer -

1.   Oxygen dissociationcurve: It is graphic respresentation of relationship between partial pressureof oxygen or p02 and percentage saturation of haemoglobin withoxygen.

2.   The graph is sigmoidas at low p02, there is reduced synthesis of oxyhaemoglobin.Percentage of oxyhaemoglobin rises with higher p02 till atabout p02 is 100mm Hg, the haemoglobin becomes fully saturatedwith 02.

3.   Further rise in p02 cannotincrease the value of oxyhaem-oglobin as the blood is already saturated withit.

 

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